In randomised trials, adults who ate the larger share of their daily calories earlier in the day lost slightly more weight over about 12 weeks than adults who ate more of them later.
Low certainty
Further research is likely to change this.Who this is about
adults with overweight or obesity in weight-loss trials
Practical note
The pooled difference was about 1.2 to 1.8 kg over roughly 12 weeks. Liu 2024 graded this outcome low certainty (4 RCTs, 272 participants); graded low here for risk of bias and imprecision.
Safety note
The trials mostly paired the timing change with an energy-reduced diet; the effect of timing alone at the same intake is less certain.
Sources
- Supports “consuming the majority of calories earlier in the day resulted in more weight loss compared with consuming them later in the day (MD, –1.75 kg; 95% CI, –2.37 to –1.13 kg;” (Results, Calorie Distribution) Liu HY, Eso AA, Cook N, O'Neill HM, Albarqouni L. 2024. JAMA Network Open. Meal Timing and Anthropometric and Metabolic Outcomes: A Systematic Review and Meta-Analysis. CC BY 4.0; credit Liu et al., JAMA Network Open 2024
- Supports “in the context of an energy-reduced diet, distributing energy intake with a focus on earlier intake resulted in significantly greater weight loss (-1.23 kg; 95% CI 2.40, -0.06, p = 0.04)” (Abstract) Young IE, Poobalan A, Steinbeck K, O'Connor HT, Parker HM. 2023. Obesity Reviews. Distribution of energy intake across the day and weight loss: A systematic review and meta-analysis. CC BY-NC-ND 4.0; credit Young et al., Obesity Reviews 2023; Courtesy of the U.S. National Library of Medicine
- Context “the effect sizes found were small and of uncertain clinical importance. High heterogeneity and risk of bias among included studies led to concerns about the certainty of the underpinning evidence.” (Abstract, Conclusions and relevance) Liu HY, Eso AA, Cook N, O'Neill HM, Albarqouni L. 2024. JAMA Network Open. Meal Timing and Anthropometric and Metabolic Outcomes: A Systematic Review and Meta-Analysis. CC BY 4.0; credit Liu et al., JAMA Network Open 2024