In randomised trials of adults with chronic pain, cupping was followed by lower short-term pain scores than no treatment, but the difference compared with sham cupping was small and not statistically significant; cupping may help people living well with chronic pain, though the trials are at high risk of bias.
Low certainty
Further research is likely to change this.Who this is about
adults with chronic pain, mainly chronic musculoskeletal pain
Practical note
Graded low: the 2020 meta-analysis pooled 18 trials with 1172 participants, most limited by risk of bias and clinical heterogeneity, and the 2025 meta-analysis found very high heterogeneity (I2 94%); patients cannot easily be blinded, and the sham comparison did not reach significance. The 2025 review found no clear improvement in functional disability.
Safety note
Adverse events were more frequent with cupping than with no treatment. Reported side effects include persistent skin discoloration, scars, burns and infections. People living with chronic pain may wish to discuss cupping with their health care provider.
Sources
- Supports “Meta-analyses found large short-term effects of cupping on pain intensity compared to no treatment (standardized mean difference [SMD] = -1.03; 95% confidence interval [CI] = -1.41, -.65), but no significant effects compared to sham cupping (SDM = -.27; 95% CI = -.58, .05)” (Abstract) Cramer H, Klose P, Teut M, Rotter G, Ortiz M, Anheyer D, Linde K, Brinkhaus B. 2020. The Journal of Pain. Cupping for Patients With Chronic Pain: A Systematic Review and Meta-Analysis. publisher copyright; metadata and short quotes only; Courtesy of the U.S. National Library of Medicine
- Supports “cupping therapy (standardised mean difference (SMD)=-1.17; 95% CI=-1.93 to -0.42; p=0.002; I2=94%) had a significant reduction effect on patients with CMP's pain intensity” (Abstract, Results) Jia Y, Dong X, Chai Y, Bai Z, Sun T, Hou X. 2025. BMJ Open. Effects of cupping therapy on chronic musculoskeletal pain and collateral problems: a systematic review and meta-analysis. CC BY-NC 4.0; credit Jia et al., BMJ Open 2025; Courtesy of the U.S. National Library of Medicine
- Context “Of the 18 included trials (n =1,172), most were limited by clinical heterogeneity and risk of bias.” (Abstract) Cramer H, Klose P, Teut M, Rotter G, Ortiz M, Anheyer D, Linde K, Brinkhaus B. 2020. The Journal of Pain. Cupping for Patients With Chronic Pain: A Systematic Review and Meta-Analysis. publisher copyright; metadata and short quotes only; Courtesy of the U.S. National Library of Medicine
- Context “But cupping therapy had no improvement effects on functional disability” (Abstract, Results) Jia Y, Dong X, Chai Y, Bai Z, Sun T, Hou X. 2025. BMJ Open. Effects of cupping therapy on chronic musculoskeletal pain and collateral problems: a systematic review and meta-analysis. CC BY-NC 4.0; credit Jia et al., BMJ Open 2025; Courtesy of the U.S. National Library of Medicine